Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713615 | 0.81 | SIGMAR1 (0.47) | SIGMAR1ACP3SMN1; SMN2ADH1BADH1C | |
| SCHEMBL7275121 | 0.81 | SIGMAR1 (0.43) | SIGMAR1ACP3SMN1; SMN2ADH1BADH1C | |
| SCHEMBL7275120 | 0.81 | SIGMAR1 (0.43) | SIGMAR1ACP3SMN1; SMN2ADH1BADH1C | |
| SCHEMBL11541322 | 0.80 | SIGMAR1 (0.39) | SIGMAR1ACP3SMN1; SMN2ADH1BADH1C | |
| SCHEMBL6601685 | 0.79 | SIGMAR1 (0.49) | SIGMAR1ACP3SMN1; SMN2POLBMEN1 | |
| SCHEMBL6601690 | 0.79 | SIGMAR1 (0.49) | SIGMAR1ACP3SMN1; SMN2POLBMEN1 | |
| SCHEMBL8399378 | 0.79 | GAA (0.44) | SIGMAR1ACP3SMN1; SMN2IDO1THRB | |
| SCHEMBL7346313 | 0.73 | SIGMAR1 (0.55) | SIGMAR1ACP3SMN1; SMN2POLBMEN1 | |
| SCHEMBL7746605 | 0.73 | SIGMAR1 (0.55) | SIGMAR1ACP3SMN1; SMN2POLBMEN1 | |
| SCHEMBL9787793 | 0.69 | CTRB1 (0.52) | SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |