Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129593 | 0.85 | CTSC (0.48) | GAAMAPTCPA1CPB1CPA3 | |
| SCHEMBL17328999 | 0.85 | LMNA (0.52) | MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7275120 | 0.79 | SIGMAR1 (0.43) | CPA3ACP3SMN1; SMN2SIGMAR1THRB | |
| SCHEMBL3713615 | 0.79 | SIGMAR1 (0.47) | MAPTACP3SMN1; SMN2SIGMAR1MCL1 | |
| SCHEMBL8399376 | 0.79 | SIGMAR1 (0.43) | MAPTACP3SMN1; SMN2SIGMAR1THRB | |
| SCHEMBL7275121 | 0.79 | SIGMAR1 (0.43) | CPA3ACP3SMN1; SMN2SIGMAR1THRB | |
| SCHEMBL6601685 | 0.76 | SIGMAR1 (0.49) | GAAMAPTACP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL6601690 | 0.76 | SIGMAR1 (0.49) | GAAMAPTACP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7211198 | 0.75 | PPID (0.46) | GAAMAPTSMN1; SMN2LMNAMCL1 | |
| SCHEMBL60484 | 0.75 | GAA (0.62) | GAAMAPTCPA1CPB1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |