Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 14/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 14/20 | 0.53 |
| ▸ | MPL | P40238 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25261119 | 0.87 | FEN1 (0.58) | FEN1ALOX5APMPLKDM1ACYP11B1 | |
| SCHEMBL38614 | 0.80 | FEN1 (0.47) | FEN1ALOX5AP | |
| SCHEMBL503341 | 0.78 | ALOX5AP (0.43) | FEN1ALOX5APKDM1ACYP11B1 | |
| SCHEMBL15862910 | 0.78 | FEN1 (0.52) | FEN1ALOX5APMPLKDM1ACYP11B1 | |
| SCHEMBL3717630 | 0.78 | FEN1 (0.50) | FEN1ALOX5APMPLKDM1ACYP11B1 | |
| SCHEMBL31356754 | 0.78 | FEN1 (0.55) | FEN1ALOX5APMPLKDM1A | |
| SCHEMBL4943336 | 0.78 | FEN1 (0.49) | FEN1ALOX5APMPLKDM1A | |
| SCHEMBL4608643 | 0.77 | KDM1A (0.41) | FEN1ALOX5APMPLKDM1AMAOB | |
| SCHEMBL31063587 | 0.76 | FEN1 (0.48) | FEN1ALOX5APMPLKDM1A | |
| SCHEMBL31562095 | 0.76 | FEN1 (0.48) | FEN1ALOX5APMPLKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |