SCHEMBL38614

SCHEMBL38614

Fc1ccc(-c2ccc(Br)cn2)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 5/20 0.47
ALOX5AP P20292 5/20 0.47
DHODH Q02127 1/20 0.43
KMO O15229 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
GRM2 Q14416 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
ALPL P05186 2/20 0.37
NPC1 O15118 2/20 0.36
GAA P10253 1/20 0.36
NFKB1 P19838 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19248543 0.85 KMO (0.47) FEN1ALOX5APDHODHKMOL3MBTL1
SCHEMBL30540118 0.85 KMO (0.47) FEN1ALOX5APDHODHKMOL3MBTL1
SCHEMBL503341 0.83 ALOX5AP (0.43) FEN1ALOX5APGRM2NPC1GAA
SCHEMBL3713639 0.80 FEN1 (0.53) FEN1ALOX5AP
SCHEMBL17630035 0.79 EGLN2 (0.43) FEN1ALOX5APGABRG2GABRB3GABRA5
SCHEMBL23319259 0.79 KMO (0.46) FEN1ALOX5APDHODHKMOL3MBTL1
SCHEMBL12807354 0.79 DHODH (0.43) FEN1ALOX5APDHODHKMOL3MBTL1
SCHEMBL15574132 0.79 DHODH (0.55) DHODHKMOL3MBTL1CASP3SENP8
SCHEMBL29463697 0.79 DHODH (0.55) DHODHKMOL3MBTL1CASP3SENP8
SCHEMBL2407760 0.78 NPC1 (0.53) FEN1ALOX5APDHODHL3MBTL1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209854-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209854-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
WO-2019158453-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-22 WO disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
US-10000517-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-19 US disclosed
US-10000517-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-19 US disclosed
US-20100072886-A1 Metal-Containing Dendrimers ISIS INNOVATION LIMITED (GB) 2010-03-25 US disclosed
US-7592074-B2 Metal-containing dendrimers ISIS INNOVATION LIMITED (GB) 2009-09-22 US disclosed
US-7332232-B2 OLEDs utilizing multidentate ligand systems UNIVERSAL DISPLAY CORPORATION (US) 2008-02-19 US disclosed
US-7332232-B2 OLEDs utilizing multidentate ligand systems UNIVERSAL DISPLAY CORPORATION (US) 2008-02-19 US disclosed
US-20050164029-A1 Reactive dendrimers CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2005-07-28 US disclosed
EP-1546284-A1 REACTIVE DENDRIMERS ISIS INNOVATION LIMITED (GB) 2005-06-29 EP disclosed
US-20040137263-A1 Metal-containing dendrimers CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2004-07-15 US disclosed
WO-2004020547-A1 REACTIVE DENDRIMERS ISIS INNOVATION LIMITED (GB) 2004-03-11 WO disclosed
EP-1366113-A1 METAL-CONTAINING DENDRIMERS ISIS INNOVATION LIMITED (GB) 2003-12-03 EP disclosed
WO-2002066552-A1 METAL-CONTAINING DENDRIMERS ISIS INNOVATION LIMITED (GB) 2002-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10000517-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 FEN1 925/4885ALOX5AP 502/4885DHODH 855/4885
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC FEN1 1267/4885ALOX5AP 3447/4885DHODH 3418/4885
US-20230209854-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME OCIAD1, OCIAD2, ALDH1A2 FEN1 1399/4885ALOX5AP 3536/4885DHODH 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.