Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.43 |
| ▸ | FEN1 | P39748 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38614 | 0.83 | FEN1 (0.47) | ALOX5APFEN1NPC1GAANFKB1 | |
| SCHEMBL16502032 | 0.80 | PTGS2 (0.40) | KDM1ACYP11B1PTGS2 | |
| SCHEMBL2407760 | 0.78 | NPC1 (0.53) | ALOX5APFEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3713639 | 0.78 | FEN1 (0.53) | ALOX5APFEN1KDM1ACYP11B1 | |
| SCHEMBL387551 | 0.77 | FEN1 (0.51) | ALOX5APFEN1NPC1GAANFKB1 | |
| SCHEMBL17630035 | 0.77 | EGLN2 (0.43) | ALOX5APFEN1KDM1ACYP11B1 | |
| SCHEMBL27808852 | 0.77 | NPC1 (0.37) | ALOX5APFEN1NPC1GAANFKB1 | |
| SCHEMBL13985937 | 0.76 | CCR1 (0.58) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL2653973 | 0.76 | GABRG2 (0.43) | ALOX5APFEN1NPC1GAANFKB1 | |
| SCHEMBL2405729 | 0.76 | NUDT1 (0.41) | ALOX5APFEN1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| EP-2207784-A1 | LUMINOPHORES | University of York (GB) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009040551-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009040551-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | ALOX5AP 1669/4885FEN1 450/4885NPC1 3850/4885 |
| US-20100317851-A1 | LUMINOPHORES | PPOX, CRY1, MPO | ALOX5AP 1531/4885FEN1 619/4885NPC1 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.