SCHEMBL4943336

SCHEMBL4943336

Fc1ccc(-c2ccc(C(F)(F)F)cn2)c(F)c1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 12/20 0.49
ALOX5AP P20292 12/20 0.49
MPL P40238 1/20 0.48
KDM1A O60341 1/20 0.44
PKM P14618 1/20 0.43
DHODH Q02127 1/20 0.41
KMO O15229 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31562095 0.98 FEN1 (0.48) FEN1ALOX5APMPLKDM1APKM
SCHEMBL31063587 0.98 FEN1 (0.48) FEN1ALOX5APMPLKDM1APKM
SCHEMBL31063682 0.98 FEN1 (0.48) FEN1ALOX5APMPLKDM1APKM
SCHEMBL38652286 0.94 FEN1 (0.45) FEN1ALOX5APMPLKDM1APKM
SCHEMBL30747792 0.94 FEN1 (0.46) FEN1ALOX5APMPLKDM1APKM
SCHEMBL31226795 0.94 FEN1 (0.45) FEN1ALOX5APMPLKDM1APKM
SCHEMBL25261119 0.90 FEN1 (0.58) FEN1ALOX5APMPLKDM1ANPSR1
SCHEMBL30433595 0.88 FEN1 (0.51) FEN1ALOX5APKDM1A
SCHEMBL30712826 0.87 KDM1A (0.53) FEN1ALOX5APMPLKDM1APKM
SCHEMBL29627077 0.84 GRM2 (0.47) FEN1ALOX5APMPLKDM1AKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772210-A Iridium complex and preparation method and application thereof 深圳市第二人民医院(深圳市转化医学研究院) 2024-10-15 CN claimed
CN-113195728-B Pharmaceutical process and intermediates 阿斯利康(瑞典)有限公司 2024-07-16 CN claimed
US-20240124770-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE BEIJING NORMAL UNIVERSITY (CN) 2024-04-18 US claimed
CN-117430643-A Preparation method of ionic iridium (III) complex photooxidation reduction catalyst 云南贵金属实验室有限公司 2024-01-23 CN claimed
CN-116768788-A Method for continuously synthesizing pyridine compound by adopting micro-channel reaction device through photoinduction 南京工业大学 2023-09-19 CN claimed
CN-116744909-A Metal organic frameworks deliver small and biological macromolecules for cancer immunotherapy 芝加哥大学 2023-09-12 CN claimed
EP-4138784-A1 METAL-ORGANIC FRAMEWORKS DELIVER SMALL MOLECULES AND BIOMACROMOLECULES FOR CANCER IMMUNOTHERAPY The University of Chicago (US) 2023-03-01 EP claimed
WO-2022166889-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE 北京师范大学 2022-08-11 WO claimed
CN-114751919-A Cyclobutane fused spiro indoline compound as well as preparation method and application thereof 华南理工大学 2022-07-15 CN claimed
CN-106478733-A A kind of ionic type iridium metal complex electroluminescent material and its application 中南大学 2017-03-08 CN claimed
WO-2026107178-A1 GLOBAL AFFINITY PROFILING OF MOLECULAR INTERACTIONS USING COMPETITIVE ENRICHMENT CORNELL UNIVERSITY (US) 2026-05-21 WO disclosed
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-21 US disclosed
EP-4294781-B1 CATALYTIC METHOD FOR THE PREPARATION OF PERFLUOROALKOXY-SUBSTITUTED ARENES AND HETEROARENES UNIV BERLIN FREIE (DE) 2026-05-20 EP disclosed
US-12624033-B2 KRAS inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-12 US disclosed
EP-4735439-A1 KRAS INHIBITORS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
US-20100144046-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION BIO-RAD LABORATORIES, INC. (US) 2010-06-10 US disclosed
US-20100144046-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION BIO-RAD LABORATORIES, INC. (US) 2010-06-10 US disclosed
US-7399857-B2 Synthesis of organometallic cyclometallated transition metal complexes EASTMAN KODAK COMPANY (US) 2008-07-15 US disclosed
US-20060224007-A1 Synthesis of organometallic cyclometallated transition metal complexes EASTMAN KODAK COMPANY 2006-10-05 US disclosed
US-20060223997-A1 Synthesis of organometallic cyclometallated transition metal complexes EASTMAN KODAK COMPANY 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144046-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION CAD, NCLN, CCL5 FEN1 653/4885ALOX5AP 2775/4885MPL 1568/4885
US-20060223997-A1 Synthesis of organometallic cyclometallated transition metal complexes IMMT, AP3M1, AP1M1 FEN1 1293/4885ALOX5AP 4102/4885MPL 1199/4885
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS CBR1, CBR3, CYC1 FEN1 878/4885ALOX5AP 2699/4885MPL 4704/4885
US-12624033-B2 KRAS inhibitors KRAS, NRAS, BRAF FEN1 1691/4885ALOX5AP 4178/4885MPL 1653/4885
US-20060224007-A1 Synthesis of organometallic cyclometallated transition metal complexes IMMT, AP3M1, AP1M1 FEN1 1293/4885ALOX5AP 4102/4885MPL 1199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.