Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686654 | 0.89 | CTSK (0.38) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL28235385 | 0.85 | CTSK (0.41) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL14660314 | 0.82 | CTSK (0.43) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL723335 | 0.81 | SYK (0.55) | CTSKCTSSMEN1KMT2ACA1 | |
| SCHEMBL1979479 | 0.80 | CTSK (0.45) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL29382780 | 0.80 | CTSK (0.41) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1979477 | 0.80 | CTSK (0.45) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL88462 | 0.80 | CTSK (0.41) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL2837383 | 0.80 | CTSK (0.45) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL18205347 | 0.78 | CTSK (0.41) | CTSKCTSSMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844687-B | The amino-acid ester prodrug of alkyl amino-substituted dicyan yl pyrimidines and they | 拜耳知识产权有限责任公司 | 2019-04-02 | — | — | CN | disclosed |
| US-9783571-B2 | Isolation of cysteine containing peptides | MARTIN WARHAM LANCE (US) | 2017-10-10 | — | — | US | disclosed |
| US-20150158905-A1 | Isolation of Cysteine Containing Peptides | MARTIN WARHAM LANCE (US) | 2015-06-11 | — | — | US | disclosed |
| EP-2694528-A1 | ISOLATION OF CYSTEINE CONTAINING PEPTIDES | Martin-Protean, LLC (US) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012138920-A1 | ISOLATION OF CYSTEINE CONTAINING PEPTIDES | MARTIN-PROTEAN, LLC (US) | 2012-10-11 | — | — | WO | disclosed |
| US-20120122820-A1 | PRODRUGS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT | 2012-05-17 | — | — | US | disclosed |
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122820-A1 | PRODRUGS AND THE USE THEREOF | TPMT, DPP4, PYGL | CTSK 1992/4885CTSS 2703/4885MEN1 1638/4885 |
| US-20150158905-A1 | Isolation of Cysteine Containing Peptides | LNPEP, CSTB, CPB1 | CTSK 415/4885CTSS 88/4885MEN1 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.