Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709889 | 0.86 | GPR119 (0.45) | GPR119TLR9TLR8TLR7 | |
| SCHEMBL3720029 | 0.83 | KDM4E (0.45) | GPR119PIK3CDJAK2JAK1TYK2 | |
| SCHEMBL3714938 | 0.83 | KDM1A (0.50) | GPR119PIK3CDPDE4B | |
| SCHEMBL3708950 | 0.81 | GPR119 (0.45) | GPR119 | |
| SCHEMBL3651433 | 0.80 | HRH1 (0.44) | GPR119 | |
| SCHEMBL3648875 | 0.80 | HRH1 (0.46) | GPR119 | |
| SCHEMBL3717758 | 0.80 | TLR9 (0.47) | GPR119PIK3CDJAK2JAK1TLR9 | |
| SCHEMBL3718944 | 0.80 | GPR119 (0.42) | GPR119PIK3CDJAK2JAK1TYK2 | |
| SCHEMBL3711292 | 0.79 | HRH1 (0.51) | — | |
| SCHEMBL3715446 | 0.77 | HRH1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |