Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711822 | 0.79 | CCR6 (0.60) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3713561 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL7259691 | 0.76 | AXL (0.53) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3721360 | 0.76 | RAB9A (0.51) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3331112 | 0.76 | UBE2I (0.78) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3711881 | 0.75 | JMJD6 (0.51) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3720931 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL9219906 | 0.74 | L3MBTL1 (0.55) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3719963 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBHPGDMAPT | |
| SCHEMBL3715455 | 0.73 | KDM1A (0.57) | ALDH1A1KDM4EPOLBHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |