Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | UBE2I | P63279 | 10/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 10/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 10/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 10/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720634 | 0.88 | KDM4E (0.49) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL3713561 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL3717261 | 0.78 | MAPT (0.53) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL3715096 | 0.77 | HPGD (0.45) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL3709546 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL3711258 | 0.77 | DCTPP1 (0.47) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL3331112 | 0.77 | UBE2I (0.78) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL3713427 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL3711261 | 0.75 | CASP1 (0.42) | ALDH1A1KDM4EHPGDSMN1; SMN2POLB | |
| SCHEMBL3711244 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |