Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711270 | 0.79 | PIK3CA (0.61) | KDM4EALDH1A1HPGD | |
| SCHEMBL569249 | 0.79 | ALDH1A1 (0.59) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL18706065 | 0.79 | CSNK2A1 (0.57) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3715743 | 0.78 | ALDH1A1 (0.50) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL732748 | 0.78 | KDM4E (0.51) | KDM4EMEN1KMT2ANPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29890892 | 0.77 | ALDH1A1 (0.57) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL29371765 | 0.74 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL14479830 | 0.74 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10144355 | 0.74 | MAPT (0.52) | PPARAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL13277358 | 0.74 | ALDH1A1 (0.46) | KDM4EMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |