Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 19/20 | 0.39 |
| ▸ | STK17B | O94768 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182957 | 0.89 | STK17A (0.38) | STK17ASTK17BALDH1A1L3MBTL1 | |
| SCHEMBL3715707 | 0.82 | STK17B (0.38) | STK17ASTK17BALDH1A1L3MBTL1 | |
| SCHEMBL3715708 | 0.82 | STK17B (0.38) | STK17ASTK17BALDH1A1L3MBTL1 | |
| SCHEMBL1284631 | 0.78 | TBK1 (0.44) | STK17ASTK17BALDH1A1 | |
| SCHEMBL12984819 | 0.76 | ALDH1A1 (0.35) | STK17ASTK17BALDH1A1L3MBTL1 | |
| SCHEMBL12984823 | 0.76 | ALDH1A1 (0.35) | STK17ASTK17BALDH1A1L3MBTL1 | |
| SCHEMBL13195356 | 0.76 | KMT2A (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL1233615 | 0.76 | CSNK1A1 (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL1233630 | 0.76 | CSNK1A1 (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL4182956 | 0.75 | CRHR1 (0.37) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403853-B1 | PYRROLOPYRIMIDINES USED AS KINASE INHIBITORS | MEDICAL RES COUNCIL TECHNOLOGY (GB) | 2013-08-14 | — | — | EP | disclosed |
| WO-2010100431-A1 | PYRROLOPYRIMIDINES USED AS KINASE INHIBITORS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-09-10 | — | — | WO | disclosed |