Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.38 |
| ▸ | STK17B | O94768 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715709 | 0.89 | STK17A (0.39) | STK17ASTK17BL3MBTL1ALDH1A1 | |
| SCHEMBL3715708 | 0.81 | STK17B (0.38) | STK17ASTK17BL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3715707 | 0.81 | STK17B (0.38) | STK17ASTK17BL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1284631 | 0.79 | TBK1 (0.44) | STK17ASTK17BKDM4EALDH1A1LMNA | |
| SCHEMBL12984819 | 0.77 | ALDH1A1 (0.35) | STK17ASTK17BL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL12984823 | 0.77 | ALDH1A1 (0.35) | STK17ASTK17BL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13195356 | 0.77 | KMT2A (0.35) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL4526451 | 0.76 | CRHR1 (0.37) | L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL4182956 | 0.76 | CRHR1 (0.37) | L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL1937548 | 0.76 | STK17A (0.54) | STK17ASTK17BL3MBTL1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029145-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | Novartis Ag (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007140222-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2007-12-06 | — | — | WO | disclosed |