Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713943 | 0.90 | MAPK1 (0.45) | MAPK1SMN1; SMN2ACP1MMP2MMP8 | |
| SCHEMBL3721164 | 0.88 | PARP1 (0.47) | PARP1BCHEMAOAACHEMAOB | |
| SCHEMBL3709302 | 0.88 | BCHE (0.44) | SMN1; SMN2ACP1PARP1BCHEMAOA | |
| SCHEMBL3716618 | 0.88 | MMP2 (0.48) | MMP2MMP8MMP13 | |
| SCHEMBL3717015 | 0.85 | ACP1 (0.42) | MAPK1SMN1; SMN2ACP1MMP2MMP8 | |
| SCHEMBL3711313 | 0.85 | MAPK1 (0.49) | MAPK1SMN1; SMN2ACP1PARP1MMP2 | |
| SCHEMBL3710611 | 0.85 | ACACB (0.47) | MAPK1SMN1; SMN2ACP1BCHEMAOA | |
| SCHEMBL3713515 | 0.83 | MAPK1 (0.47) | MAPK1SMN1; SMN2PARP1MMP2MMP8 | |
| SCHEMBL3714493 | 0.83 | JAK1 (0.53) | MMP2MMP8MMP13JAK2 | |
| SCHEMBL3711281 | 0.83 | ABL1 (0.45) | MAPK1SMN1; SMN2ACP1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |