Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715918 | 0.88 | MAPK1 (0.45) | BCHEMAOAACHEMAOBPARP1 | |
| SCHEMBL3715992 | 0.85 | MAPK1 (0.43) | JAK2L3MBTL1ACP1TSHRRAB9A | |
| SCHEMBL3709357 | 0.84 | ACP1 (0.53) | PTGS2ACP1TSHRSMN1; SMN2 | |
| SCHEMBL3721164 | 0.84 | PARP1 (0.47) | BCHEMAOAACHEMAOBPARP1 | |
| SCHEMBL3711316 | 0.84 | ALK (0.40) | L3MBTL1 | |
| SCHEMBL3710995 | 0.82 | L3MBTL1 (0.39) | JAK2L3MBTL1ACP1TSHRRAB9A | |
| SCHEMBL3721238 | 0.82 | EPHX2 (0.42) | L3MBTL1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL3716618 | 0.81 | MMP2 (0.48) | — | |
| SCHEMBL3715458 | 0.81 | L3MBTL1 (0.37) | JAK2L3MBTL1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL3712000 | 0.80 | MAPK1 (0.36) | JAK2L3MBTL1ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |