Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717217 | 0.89 | LMNA (0.36) | SCN9ASCN7AKCNH2SCN5ASCN2A | |
| SCHEMBL3716838 | 0.89 | ACACB (0.33) | XDHTLR8SCN9AACACBSCN7A | |
| SCHEMBL3721301 | 0.88 | PPARG (0.35) | TLR8ACACBSCN7AKCNH2SCN5A | |
| SCHEMBL3719990 | 0.86 | LMNA (0.37) | XDHTLR8SCN9AACACBSCN7A | |
| SCHEMBL3719435 | 0.86 | TLR8 (0.37) | XDHTLR8SCN9AACACBALDH1A1 | |
| SCHEMBL3719552 | 0.83 | PDE3B (0.34) | XDHACACBALDH1A1MAPTHDAC1 | |
| SCHEMBL3727015 | 0.83 | PPARG (0.35) | SCN9AACACBSCN7AKCNH2PDE4B | |
| SCHEMBL3724297 | 0.82 | ACACB (0.38) | TLR8ACACBPDE10AALDH1A1MAPT | |
| SCHEMBL3721410 | 0.82 | MAPT (0.36) | PDE10AALDH1A1MAPTTHRB | |
| SCHEMBL3716743 | 0.82 | PDE4B (0.49) | XDHTLR8SCN9AACACBSCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |