Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721301 | 0.93 | PPARG (0.35) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL3721410 | 0.91 | MAPT (0.36) | LMNAMAPTALDH1A1GAATDP1 | |
| SCHEMBL3716745 | 0.89 | XDH (0.35) | MAPTALDH1A1SCN7AKCNH2SCN5A | |
| SCHEMBL3716838 | 0.87 | ACACB (0.33) | MAPTGAASCN7AKCNH2SCN5A | |
| SCHEMBL3721614 | 0.87 | ACACB (0.36) | MAPTALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3727015 | 0.85 | PPARG (0.35) | PPARGSCN7AKCNH2SCN9APDE4B | |
| SCHEMBL3726780 | 0.85 | PPARG (0.36) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL3726083 | 0.85 | GLA (0.39) | LMNACSF1RMAPTHPGDTDP1 | |
| SCHEMBL3719602 | 0.83 | SCN7A (0.34) | HPGDPPARGSCN7AKCNH2SCN9A | |
| SCHEMBL3719552 | 0.82 | PDE3B (0.34) | LMNAMAPTALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |