Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 5/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719602 | 0.95 | SCN7A (0.34) | PPARGKCNH2SCN7ASCN9AACACB | |
| SCHEMBL3725386 | 0.88 | ACACB (0.39) | PPARGACACAACACB | |
| SCHEMBL3721103 | 0.87 | PARP10 (0.37) | PPARGACACAACACB | |
| SCHEMBL3719580 | 0.86 | ACACB (0.38) | KCNH2SCN7AACACAACACB | |
| SCHEMBL3717503 | 0.86 | KCNH2 (0.36) | PPARGKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL3717217 | 0.85 | LMNA (0.36) | PPARGKCNH2PDE4BSCN7ASCN9A | |
| SCHEMBL3721301 | 0.85 | PPARG (0.35) | PPARGKCNH2PDE4BSCN7AACACB | |
| SCHEMBL3726881 | 0.83 | HPGD (0.40) | KCNH2SCN7AACACAACACB | |
| SCHEMBL3716745 | 0.83 | XDH (0.35) | KCNH2PDE4BSCN7ASCN9AACACB | |
| SCHEMBL3720428 | 0.82 | ACACB (0.47) | PPARGACACAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |