Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.47 |
| ▸ | ACACA | Q13085 | 9/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724748 | 0.88 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL3720775 | 0.85 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL3721369 | 0.85 | ALDH1A1 (0.50) | ACACBACACA | |
| SCHEMBL3798078 | 0.83 | ALOX5 (0.57) | ACACBACACA | |
| SCHEMBL3719663 | 0.83 | ACACB (0.56) | ACACBACACA | |
| SCHEMBL3721544 | 0.82 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL3724565 | 0.82 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL3722350 | 0.82 | TAS1R3 (0.56) | ACACBACACA | |
| SCHEMBL3723711 | 0.82 | ACACB (0.41) | ACACBACACA | |
| SCHEMBL3727288 | 0.81 | ACACB (0.46) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |