Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.38 |
| ▸ | ACACA | Q13085 | 6/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TEC | P42680 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717202 | 0.88 | ACACB (0.38) | ACACBACACAFFAR4MAPK1CYP1A2 | |
| SCHEMBL3726328 | 0.85 | ACACB (0.40) | ACACBACACAMAPK1POLBCYP1A2 | |
| SCHEMBL3727055 | 0.81 | ACACB (0.56) | ACACBACACA | |
| SCHEMBL3728875 | 0.80 | ACACB (0.44) | ACACBACACAFFAR4 | |
| SCHEMBL3728844 | 0.79 | FFAR4 (0.44) | ACACBACACAFFAR4 | |
| SCHEMBL3722663 | 0.79 | ACACB (0.43) | ACACBACACAFFAR4RAB9A | |
| Hydrochloric Acid SCHEMBL3722701 | 0.78 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL3719466 | 0.77 | ACACB (0.41) | ACACBACACAFFAR4GAA | |
| SCHEMBL3719559 | 0.76 | ACACB (0.44) | ACACBACACATEC | |
| SCHEMBL3717200 | 0.75 | ACACB (0.35) | ACACBACACACYP1A2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |