Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727055 | 0.91 | ACACB (0.56) | ACACBMTNR1AMTNR1BACACA | |
| Hydrochloric Acid SCHEMBL3722701 | 0.89 | ACACB (0.44) | ACACBMTNR1AMTNR1BACACAMEN1 | |
| SCHEMBL3722663 | 0.89 | ACACB (0.43) | ACACBMTNR1AMTNR1BACACAMEN1 | |
| SCHEMBL3719466 | 0.86 | ACACB (0.41) | ACACBMTNR1AMTNR1BACACAMEN1 | |
| SCHEMBL3728844 | 0.84 | FFAR4 (0.44) | ACACBMTNR1AMTNR1BACACAFFAR4 | |
| SCHEMBL3717202 | 0.82 | ACACB (0.38) | ACACBACACAMEN1KMT2AFFAR4 | |
| SCHEMBL3719633 | 0.81 | ACACB (0.53) | ACACBMTNR1AMTNR1BACACA | |
| SCHEMBL3717201 | 0.80 | ACACB (0.38) | ACACBACACAFFAR4 | |
| SCHEMBL3727674 | 0.80 | MTNR1A (0.58) | ACACBMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL3727352 | 0.79 | MTNR1A (0.50) | ACACBMTNR1AMTNR1BACACACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |