Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 12/20 | 0.43 |
| ▸ | ACACA | Q13085 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722663 | 0.88 | ACACB (0.43) | FFAR4ACACBACACAKDM4EMTNR1A | |
| SCHEMBL3727055 | 0.85 | ACACB (0.56) | ACACBACACAKDM4EMTNR1AMTNR1B | |
| SCHEMBL3719466 | 0.85 | ACACB (0.41) | FFAR4ACACBACACAKDM4EMTNR1A | |
| SCHEMBL3728875 | 0.84 | ACACB (0.44) | FFAR4ACACBACACAMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3722701 | 0.82 | ACACB (0.44) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL13076818 | 0.79 | ACACB (0.43) | ACACBACACAEGLN1 | |
| SCHEMBL3717202 | 0.79 | ACACB (0.38) | FFAR4ACACBACACA | |
| SCHEMBL3717201 | 0.79 | ACACB (0.38) | FFAR4ACACBACACA | |
| SCHEMBL3726328 | 0.79 | ACACB (0.40) | ACACBACACA | |
| SCHEMBL3719633 | 0.76 | ACACB (0.53) | ACACBACACAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |