Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719466 | 0.91 | ACACB (0.41) | ACACBMTNR1AMTNR1BKDM4EFFAR4 | |
| Hydrochloric Acid SCHEMBL3722701 | 0.90 | ACACB (0.44) | ACACBMTNR1AMTNR1BACACAMEN1 | |
| SCHEMBL3727055 | 0.90 | ACACB (0.56) | ACACBMTNR1AMTNR1BKDM4EACACA | |
| SCHEMBL3728875 | 0.89 | ACACB (0.44) | ACACBMTNR1AMTNR1BFFAR4ACACA | |
| SCHEMBL3728844 | 0.88 | FFAR4 (0.44) | ACACBMTNR1AMTNR1BKDM4EFFAR4 | |
| SCHEMBL3719633 | 0.80 | ACACB (0.53) | ACACBMTNR1AMTNR1BACACASCN9A | |
| SCHEMBL3722662 | 0.79 | ACACB (0.47) | ACACBACACASCN9A | |
| SCHEMBL3717202 | 0.79 | ACACB (0.38) | ACACBFFAR4ACACAMEN1KMT2A | |
| SCHEMBL3717201 | 0.79 | ACACB (0.38) | ACACBFFAR4ACACARAB9A | |
| SCHEMBL3717149 | 0.79 | MTNR1A (0.58) | ACACBMTNR1AMTNR1BKDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |