SCHEMBL3717211

SCHEMBL3717211

O=[N+]([O-])c1ccc(S(=O)(=O)CCO)c(C(F)(F)F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
CCR2 P41597 1/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
PKM P14618 2/20 0.43
CA2 P00918 2/20 0.43
POLB P06746 1/20 0.42
MAPT P10636 5/20 0.42
HTT P42858 4/20 0.42
PDE7A Q13946 1/20 0.41
LMNA P02545 3/20 0.40
MAPK1 P28482 2/20 0.40
HSD11B1 P28845 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716406 0.81 CA2 (0.60) ALDH1A1MEN1KMT2ACA2HTT
SCHEMBL19071925 0.81 ALDH1A1 (0.48) ALDH1A1MEN1KMT2APKMCA2
SCHEMBL27895288 0.81 PDE7A (0.48) ALDH1A1MEN1KMT2APKMCA2
SCHEMBL5713455 0.80 ALDH1A1 (0.61) ALDH1A1MEN1KMT2ACA2MAPT
SCHEMBL31219671 0.80 GPR35 (0.49) ALDH1A1MEN1KMT2ACA2MAPK1
SCHEMBL1870872 0.78 TRPV4 (0.53) ALDH1A1MEN1KMT2APKMCA2
SCHEMBL2029532 0.78 ALDH1A1 (0.46) ALDH1A1CCR2MEN1KMT2APKM
SCHEMBL6194504 0.78 PDE7A (0.49) ALDH1A1MEN1KMT2APKMCA2
SCHEMBL8142655 0.78 PDE7A (0.46) ALDH1A1MEN1KMT2APKMCA2
SCHEMBL10955111 0.77 ALDH1A1 (0.49) ALDH1A1CA2POLBPDE7AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102317378-B Fluorine containing reactive dyes Sisei printing and dyeing technology (Shanghai) Co.,Ltd. (CN) 2015-08-19 CN disclosed
WO-2010094415-A1 FLUORINE CONTAINING REACTIVE DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2010-08-26 WO disclosed