Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 5/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3714611 | 0.98 | CDK4 (0.39) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL8087820 | 0.98 | CDK4 (0.42) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL28745657 | 0.81 | HTR2A (0.44) | CDK4CCND1HTR6NOTUMDRD2 | |
| SCHEMBL31195323 | 0.81 | HTR2C (0.44) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL1136602 | 0.81 | HTR2C (0.44) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL9703835 | 0.81 | POLB (0.39) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL21047721 | 0.79 | TSHR (0.39) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL21047733 | 0.79 | TSHR (0.36) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL18379331 | 0.78 | CDK4 (0.54) | CDK4CCND1TSHRRAB9AL3MBTL1 | |
| SCHEMBL27527109 | 0.75 | TSHR (0.46) | TSHRRAB9AL3MBTL1HTR6RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647121-A3 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| EP-4647121-A2 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2025-11-12 | — | — | EP | disclosed |
| EP-4647121-A2 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2025-11-12 | — | — | EP | disclosed |
| EP-4393545-B1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2025-10-08 | — | — | EP | disclosed |
| US-20250195493-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2025-06-19 | — | — | US | disclosed |
| US-20250195493-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2025-06-19 | — | — | US | disclosed |
| US-12285422-B2 | Uses of piperidinyl-indole derivatives | NOVARTIS AG (CH) | 2025-04-29 | — | — | US | disclosed |
| US-12285422-B2 | Uses of piperidinyl-indole derivatives | NOVARTIS AG (CH) | 2025-04-29 | — | — | US | disclosed |
| US-12285422-B2 | Uses of piperidinyl-indole derivatives | NOVARTIS AG (CH) | 2025-04-29 | — | — | US | disclosed |
| EP-4393545-A3 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2024-09-25 | — | — | EP | disclosed |
| US-20020072611-A1 | Antipsychotic heterocycle compounds | BRISTOL-MYERS SQUIBB COMPANY | 2002-06-13 | — | — | US | disclosed |
| EP-1087962-A4 | PREPARATION OF HETEROARYL COMPOUNDS | LILLY CO ELI (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2001043740-A1 | ANTIPSYCHOTIC HETEROCYCLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |
| EP-1087962-A1 | PREPARATION OF HETEROARYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-1077213-A2 | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6046215-A | A PIPERIDINYLBENZOTHIOPHENES USEFUL FOR TRATING BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| WO-1999065896-A1 | PREPARATION OF HETEROARYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| US-5846982-A | Inhibition of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| EP-0812826-A1 | 1H-indole and benzo(b)thiophene derivatives with 4-(1,2,3,6-tetra:hydro:pyridinyl)- and 4-piperidinyl-groups bound to the heterocyclic ring as inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072611-A1 | Antipsychotic heterocycle compounds | HTR2C, DRD2, HTR1A | CDK4 1558/4885CCND1 547/4885TSHR 97/4885 |
| US-20250195493-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | C5, C3AR1, FCGRT | CDK4 1660/4885CCND1 1513/4885TSHR 2798/4885 |
| US-12285422-B2 | Uses of piperidinyl-indole derivatives | C5, FCGRT, C3AR1 | CDK4 2105/4885CCND1 1847/4885TSHR 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.