Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718569 | 0.85 | MAPT (0.37) | MAPTP2RX3TLR8 | |
| SCHEMBL3718483 | 0.84 | MAPT (0.38) | MAPTP2RX3 | |
| SCHEMBL3717014 | 0.84 | MAPT (0.34) | MAPTNPC1RAB9AP2RX3TLR8 | |
| SCHEMBL3720739 | 0.83 | MAPT (0.39) | MAPTNPC1RAB9AP2RX3 | |
| SCHEMBL3720742 | 0.83 | MAPT (0.37) | MAPTP2RX3TLR8 | |
| SCHEMBL3717625 | 0.79 | S1PR3 (0.36) | TLR8 | |
| SCHEMBL3727694 | 0.79 | MAPT (0.32) | MAPT | |
| SCHEMBL3720187 | 0.78 | MAPT (0.32) | MAPT | |
| SCHEMBL3720648 | 0.78 | MAPT (0.36) | MAPTP2RX3 | |
| SCHEMBL3726852 | 0.78 | P2RX3 (0.43) | MAPTP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |