Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 15/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151666 | 0.86 | POLB (0.49) | C5AR1CHRM5ALDH1A1KMT2A | |
| SCHEMBL13150765 | 0.82 | POLB (0.58) | C5AR1CHRM5KMT2A | |
| SCHEMBL14253733 | 0.72 | HTR1A (0.49) | ALDH1A1 | |
| SCHEMBL13150780 | 0.72 | ALDH1A1 (0.70) | CHRM5ALDH1A1KMT2A | |
| SCHEMBL13150794 | 0.72 | TSHR (0.66) | CHRM5ALDH1A1KMT2A | |
| SCHEMBL13150171 | 0.70 | GLRA3 (0.69) | C5AR1GLRA3GLRBKMT2A | |
| SCHEMBL13150789 | 0.70 | C5AR1 (0.48) | C5AR1CHRM5KMT2A | |
| SCHEMBL4227431 | 0.69 | CHRM1 (0.53) | CHRM5 | |
| SCHEMBL13150927 | 0.69 | C5AR1 (0.52) | C5AR1 | |
| SCHEMBL3176824 | 0.69 | PTGS1 (0.56) | CHRM5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |