Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720293 | 0.89 | GLA (0.42) | ALDH1A1RAB9ASMN1; SMN2GLATLR8 | |
| SCHEMBL3722576 | 0.88 | TLR8 (0.40) | TAAR1CYP1A2TLR8CYP3A4TSHR | |
| SCHEMBL3720365 | 0.88 | MAPT (0.41) | ALDH1A1RAB9ATAAR1CYP1A2MEN1 | |
| SCHEMBL3717202 | 0.85 | ACACB (0.38) | TAAR1CYP1A2MEN1KMT2ACYP2D6 | |
| SCHEMBL3720134 | 0.83 | ALDH1A1 (0.48) | ALDH1A1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL3728526 | 0.83 | CYP1A2 (0.36) | ALDH1A1TAAR1CYP1A2MEN1KMT2A | |
| SCHEMBL3720117 | 0.83 | LMNA (0.39) | TAAR1CYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3720042 | 0.82 | MAP4K4 (0.48) | — | |
| SCHEMBL3722383 | 0.82 | CYP1A2 (0.35) | ALDH1A1RAB9ATAAR1CYP1A2MEN1 | |
| SCHEMBL3716750 | 0.82 | CYP1A2 (0.35) | ALDH1A1RAB9ATAAR1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |