Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720725 | 0.87 | ACACB (0.38) | LMNATLR8SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL3719435 | 0.86 | TLR8 (0.37) | LMNATLR8SMN1; SMN2XDHCYP1A2 | |
| SCHEMBL3725388 | 0.86 | GLA (0.44) | LMNATECTLR8SMN1; SMN2CYP1A2 | |
| SCHEMBL3717202 | 0.85 | ACACB (0.38) | LMNATECCYP1A2CYP3A4TSHR | |
| SCHEMBL3720293 | 0.84 | GLA (0.42) | LMNATECTLR8SMN1; SMN2GLA | |
| SCHEMBL3720365 | 0.83 | MAPT (0.41) | LMNATECSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL3719990 | 0.83 | LMNA (0.37) | LMNATECTLR8XDHNPC1 | |
| SCHEMBL3717827 | 0.83 | ALDH1A1 (0.49) | LMNATLR8SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL3722383 | 0.82 | CYP1A2 (0.35) | LMNATECCYP1A2CYP3A4TSHR | |
| SCHEMBL3716750 | 0.82 | CYP1A2 (0.35) | LMNATECSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |