Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | HRH2 | P25021 | 3/20 | 0.51 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721168 | 0.92 | PRMT5 (0.56) | ALDH1A1HRH3TMEM97SIGMAR1PRMT5 | |
| SCHEMBL314343 | 0.81 | MC4R (0.60) | ALDH1A1SIGMAR1HRH1HTR1AHTR2A | |
| SCHEMBL313962 | 0.81 | HTR1A (0.57) | ALDH1A1HRH3TMEM97SIGMAR1HRH2 | |
| SCHEMBL314299 | 0.79 | SLC18A3 (0.67) | ALDH1A1HRH3SIGMAR1PRMT5WDR77 | |
| SCHEMBL3662555 | 0.78 | NPC1 (0.60) | ALDH1A1HRH3HRH2HRH1HTR1A | |
| SCHEMBL314201 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HTR1AHTR1BDRD3 | |
| SCHEMBL6677698 | 0.77 | NOTUM (0.57) | ALDH1A1NAMPTNOTUM | |
| Formic Acid SCHEMBL314781 | 0.77 | HTR1A (0.52) | ALDH1A1HRH3TMEM97SIGMAR1HRH2 | |
| SCHEMBL313776 | 0.77 | PRMT5 (0.64) | ALDH1A1HRH3SIGMAR1PRMT5WDR77 | |
| SCHEMBL3721043 | 0.76 | NOTUM (0.55) | ALDH1A1PRMT5WDR77NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026993-A | New compounds III | BIOVITRUM AB PUBL | 2011-04-20 | — | — | CN | claimed |
| US-20090176798-A1 | New compounds III | BIOVITRUM AB (SE) | 2009-07-09 | — | — | US | claimed |
| CN-102026993-A | New compounds III | BIOVITRUM AB PUBL | 2011-04-20 | — | — | CN | disclosed |
| EP-2227461-A1 | NEW COMPOUNDS III | AstraZeneca AB (Publ) (SE) | 2010-09-15 | — | — | EP | disclosed |
| US-20090176798-A1 | New compounds III | BIOVITRUM AB (SE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176798-A1 | New compounds III | BIOVITRUM AB (SE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176798-A1 | New compounds III | BIOVITRUM AB (SE) | 2009-07-09 | — | — | US | disclosed |
| WO-2009071677-A1 | NEW COMPOUNDS III | BIOVITRUM AB (PUBL) (SE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071677-A1 | NEW COMPOUNDS III | BIOVITRUM AB (PUBL) (SE) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176798-A1 | New compounds III | GPR119, FABP4, GLP1R | ALDH1A1 2912/4885HRH3 3759/4885TMEM97 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.