Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720375 | 0.93 | MCHR1 (0.35) | PARP10PARP15 | |
| SCHEMBL3722669 | 0.89 | PARP10 (0.37) | PARP10PARP15MAOAMAOB | |
| SCHEMBL3717503 | 0.87 | KCNH2 (0.36) | — | |
| SCHEMBL3717025 | 0.87 | PARP10 (0.40) | PARP10PARP15 | |
| SCHEMBL3721103 | 0.87 | PARP10 (0.37) | PARP10PARP15MAOAMAOB | |
| SCHEMBL3720495 | 0.84 | MTNR1A (0.46) | PARP10PARP15 | |
| SCHEMBL3718627 | 0.83 | ACACB (0.43) | — | |
| SCHEMBL3717501 | 0.83 | GLA (0.39) | — | |
| SCHEMBL3721908 | 0.83 | GLA (0.41) | — | |
| SCHEMBL3720089 | 0.82 | TEC (0.37) | PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |