Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720845 | 0.93 | MTNR1A (0.46) | MTNR1AMTNR1BHRH3ACACBHTR2C | |
| SCHEMBL3721288 | 0.91 | MTNR1A (0.45) | MTNR1AMTNR1BACACBHTR2CPARP15 | |
| SCHEMBL3724290 | 0.89 | MTNR1A (0.48) | MTNR1AMTNR1BHRH3ACACBHTR2C | |
| SCHEMBL3722996 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1BACACB | |
| SCHEMBL3722610 | 0.86 | ACACB (0.51) | MTNR1AMTNR1BACACBHTR2CPDE10A | |
| SCHEMBL3806067 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BACACBHTR2CKMT2A | |
| SCHEMBL3720900 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BHRH3ACACB | |
| SCHEMBL3719459 | 0.84 | PARP10 (0.37) | PARP15PARP10 | |
| SCHEMBL3720199 | 0.84 | MTNR1A (0.52) | MTNR1AMTNR1BACACBHTR2CACACA | |
| SCHEMBL3721101 | 0.84 | PDE4B (0.44) | ACACBPARP15PARP10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |