SCHEMBL371993

SCHEMBL371993

c1ccc2c3c(ccc2c1)OCCC3

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
HSD17B10 Q99714 2/20 0.53
CYP1A2 P05177 1/20 0.53
GLA P06280 1/20 0.53
CYP2C9 P11712 1/20 0.53
HPGD P15428 1/20 0.53
CYP2C19 P33261 1/20 0.53
SIRT1 Q96EB6 1/20 0.53
MAPT P10636 2/20 0.50
ACHE P22303 2/20 0.44
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
SMPD1 P17405 1/20 0.41
VDR P11473 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30003445 1.00 KDM4E (0.53) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL29670013 1.00 KDM4E (0.53) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL30505176 0.91 HPRT1 (0.47) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL372146 0.91 HPRT1 (0.47) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL7473565 0.89 KDM4E (0.56) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL30830197 0.89 KDM4E (0.56) KDM4EHSD17B10CYP1A2GLACYP2C9
Water SCHEMBL16634424 0.87 KDM4E (0.54) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL29269339 0.80 HPRT1 (0.50) KDM4EHSD17B10CYP1A2GLACYP2C9
Acetic Acid SCHEMBL11711913 0.78 KDM4E (0.50) KDM4EHSD17B10CYP1A2GLACYP2C9
SCHEMBL1143507 0.77 HTR2C (0.45) ACHEMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117580837-A Compound and organic light emitting device comprising the same 株式会社LG化学 2024-02-20 CN claimed
CN-117479566-A Composition, light emitting device including the same, and electronic device including the light emitting device 三星电子株式会社 2024-01-30 CN claimed
CN-117479565-A Light emitting device and electronic apparatus including the same 三星电子株式会社 2024-01-30 CN claimed
US-10562275-B2 Glass pane as head-up display SEKISUI CHEMICAL CO., LTD. (JP) 2020-02-18 US claimed
US-9855727-B2 Glass pane as head-up display SEKISUI CHEMICAL CO., LTD. (JP) 2018-01-02 US claimed
US-9816027-B2 Method for producing a film having luminescent particles SEKISUI CHEMICAL CO., LTD. (JP) 2017-11-14 US claimed
US-20170184845-A1 GLASS PANE AS HEAD-UP DISPLAY SEKISUI CHEMICAL CO., LTD. (JP) 2017-06-29 US claimed
EP-2595808-B1 LAMINATED GLAZING USED AS HEAD-UP-DISPLAY SAINT GOBAIN (FR) 2017-04-05 EP claimed
EP-2697336-B1 PROCESS FOR THE MANUFACTURE OF A FILM WITH LUMINOUS PARTICLES SAINT GOBAIN (FR) 2016-06-01 EP claimed
US-9314998-B2 Composite glass pane as a head-up display SAINT-GOBAIN GLASS FRANCE (FR) 2016-04-19 US claimed
EP-1410785-B1 Make-up product, combining two compositions, comprising a photochromic dye and a goniochromatic agent, respectively OREAL (FR) 2007-01-03 EP claimed
US-20040228817-A1 Makeup combining at least one photochromic dye and at least one goniochromatic agent L'OREAL (FR) 2004-11-18 US claimed
US-20040228818-A1 Cosmetic composition combining at least two dyes including at least one photochromic dye L'OREAL (FR) 2004-11-18 US claimed
EP-0755527-B1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG IND OHIO INC (US) 2000-03-15 EP claimed
EP-0755527-A4 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES INC (US) 1997-06-18 EP claimed
EP-0755527-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1997-01-29 EP claimed
US-5565147-A OPHTHALMIC LENSES TRANSITIONS OPTICAL, INC. (US) 1996-10-15 US claimed
WO-1995027914-A1 PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS PPG INDUSTRIES, INC. (US) 1995-10-19 WO claimed
US-5451344-A Opthalmic lenses or transparencies for photochromic compounds TRANSITIONS OPTICAL, INC. (US) 1995-09-19 US claimed
US-5429774-A FOR USE IN PHOTOCHROMIC ARTICLES TRANSITIONS OPTICAL, INC. (US) 1995-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040228817-A1 Makeup combining at least one photochromic dye and at least one goniochromatic agent GYPA, TYR, GLA KDM4E 4265/4885HSD17B10 358/4885CYP1A2 611/4885
US-20040228818-A1 Cosmetic composition combining at least two dyes including at least one photochromic dye CUTA, TYR, LAGE3 KDM4E 3484/4885HSD17B10 776/4885CYP1A2 2600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.