Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717024 | 0.95 | SCN7A (0.38) | MAPTSCN7AKCNH2ACACB | |
| SCHEMBL3720733 | 0.87 | ACACB (0.39) | MAPTACACAACACBP2RX3 | |
| SCHEMBL3718624 | 0.87 | ACACB (0.46) | MAPTACACAACACB | |
| SCHEMBL3717502 | 0.87 | KCNH2 (0.36) | MAPTSCN7AKCNH2PDE4APDE4D | |
| SCHEMBL3720292 | 0.83 | MAPT (0.41) | MAPTSCN7AACACALMNAACACB | |
| SCHEMBL3722666 | 0.83 | MAOA (0.37) | MAPTACACAACACB | |
| SCHEMBL3726999 | 0.82 | GPR4 (0.39) | SCN7AKCNH2KDM4CACACASLC6A2 | |
| SCHEMBL3721905 | 0.82 | EPHA2 (0.38) | ACACASLC6A4ACACB | |
| SCHEMBL3720374 | 0.82 | EGFR (0.34) | MAPTSCN7AKCNH2 | |
| SCHEMBL3719458 | 0.82 | PARP15 (0.37) | MAPTACACAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |