Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.39 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721905 | 0.95 | EPHA2 (0.38) | ACACBACACACYP2C9CYP3A4ERBB2 | |
| SCHEMBL3718624 | 0.92 | ACACB (0.46) | ACACBACACACYP2C9CYP3A4MAPT | |
| SCHEMBL3717502 | 0.88 | KCNH2 (0.36) | ERBB2EPHA2KDREPHB4MAPT | |
| SCHEMBL3723729 | 0.88 | RORC (0.40) | ACACBERBB2MAPTEGFR | |
| SCHEMBL3717278 | 0.87 | CSNK2A1 (0.39) | MAPTCYP2C19 | |
| SCHEMBL3720087 | 0.87 | MAPT (0.38) | ACACBACACAP2RX3MAPT | |
| SCHEMBL3720374 | 0.84 | EGFR (0.34) | EPHA2KDREPHB4MAPTEGFR | |
| SCHEMBL3717024 | 0.82 | SCN7A (0.38) | ACACBMAPT | |
| SCHEMBL3719949 | 0.82 | RORC (0.39) | ACACBP2RX3MAPTCYP2C19 | |
| SCHEMBL3720104 | 0.81 | ACACB (0.43) | ACACBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |