Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727138 | 0.85 | TSHR (0.34) | LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL3717723 | 0.84 | TLR8 (0.33) | ALDH1A1LMNACYP1A2CYP2C9HPGD | |
| SCHEMBL3720275 | 0.83 | LMNA (0.32) | ALDH1A1LMNACYP1A2CYP2C9HPGD | |
| SCHEMBL3720627 | 0.82 | MTNR1A (0.50) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3719892 | 0.80 | ACACB (0.32) | LMNACYP1A2CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL3720538 | 0.80 | LMNA (0.31) | LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3720159 | 0.80 | PDE4B (0.42) | ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL3727136 | 0.79 | MAPT (0.34) | — | |
| SCHEMBL3720633 | 0.78 | SMN1; SMN2 (0.33) | ALDH1A1LMNACYP1A2CYP2C9HPGD | |
| SCHEMBL3720626 | 0.76 | ACACB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |