Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 8/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720107 | 0.90 | MTNR1A (0.54) | MTNR1AMTNR1BACACBACACAKDM4E | |
| SCHEMBL3722610 | 0.88 | ACACB (0.51) | MTNR1AMTNR1BACACBHTR2CACACA | |
| SCHEMBL3724290 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BACACBHTR2CACACA | |
| SCHEMBL3721039 | 0.87 | ACACA (0.51) | MTNR1AMTNR1BACACBHTR2CACACA | |
| SCHEMBL3726174 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BACACBHTR2CSCN9A | |
| SCHEMBL3721288 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BACACBHTR2CACACA | |
| SCHEMBL3724136 | 0.85 | ACACB (0.57) | MTNR1AMTNR1BACACBACACASCN9A | |
| SCHEMBL3727682 | 0.85 | MTNR1A (0.55) | MTNR1AMTNR1BACACBSCN9A | |
| SCHEMBL3719950 | 0.84 | MTNR1A (0.38) | MTNR1AACACBACACASCN9AMCHR1 | |
| SCHEMBL3806067 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BACACBHTR2CACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |