Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726019 | 0.87 | ALDH1A1 (0.45) | — | |
| SCHEMBL3720107 | 0.85 | MTNR1A (0.54) | MTNR1AACACBACACASCN7A | |
| SCHEMBL3720199 | 0.84 | MTNR1A (0.52) | MTNR1AACACBSCN9AACACAMCHR1 | |
| SCHEMBL3720089 | 0.81 | TEC (0.37) | ACACBACACASCN7AKCNH2 | |
| SCHEMBL3726999 | 0.81 | GPR4 (0.39) | ACACBACACASCN7AKCNH2KDM4C | |
| SCHEMBL3719580 | 0.79 | ACACB (0.38) | ACACBACACASCN7AKCNH2MCHR1 | |
| SCHEMBL3720928 | 0.79 | SCN7A (0.38) | ACACBACACASCN7AKCNH2MCHR1 | |
| SCHEMBL3719947 | 0.78 | ACACA (0.42) | ACACBACACAMCHR1 | |
| SCHEMBL3717025 | 0.76 | PARP10 (0.40) | ACACBSCN7AKCNH2 | |
| SCHEMBL3727742 | 0.76 | P2RX3 (0.40) | ACACBSCN9AACACASCN7AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |