Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150378 | 0.63 | BACE1 (0.38) | — | |
| SCHEMBL2482302 | 0.60 | FFAR4 (0.35) | FFAR4 | |
| SCHEMBL1150359 | 0.60 | OPRL1 (0.43) | — | |
| SCHEMBL13482122 | 0.59 | MAOA (0.43) | — | |
| SCHEMBL7476195 | 0.59 | MAOA (0.43) | — | |
| SCHEMBL7230239 | 0.59 | MAOA (0.43) | — | |
| SCHEMBL22712771 | 0.58 | PBRM1 (0.42) | — | |
| SCHEMBL15464981 | 0.58 | NNMT (0.40) | — | |
| SCHEMBL20095868 | 0.58 | CYP11B2 (0.40) | — | |
| SCHEMBL23778811 | 0.57 | PARP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240482-A1 | CYCLIC AZAINDOLE-3-CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | Sanofi-Aventis (FR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009095162-A1 | CYCLIC AZAINDOLE-3-CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | disclosed |