Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724290 | 0.96 | MTNR1A (0.48) | MTNR1AMTNR1BHRH3ACACBSCN9A | |
| SCHEMBL3720495 | 0.93 | MTNR1A (0.46) | MTNR1AMTNR1BHRH3ACACBHTR2C | |
| SCHEMBL3806067 | 0.90 | MTNR1A (0.44) | MTNR1AMTNR1BACACBSCN9AHTR2C | |
| SCHEMBL3721082 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1BHRH3ACACBSCN9A | |
| SCHEMBL3721288 | 0.86 | MTNR1A (0.45) | MTNR1AMTNR1BACACBHTR2CSRC | |
| SCHEMBL3720375 | 0.84 | MCHR1 (0.35) | HRH3 | |
| SCHEMBL3720199 | 0.84 | MTNR1A (0.52) | MTNR1AMTNR1BACACBSCN9AHTR2C | |
| SCHEMBL3719600 | 0.84 | PDE4B (0.48) | SCN9ASRCMEN1KMT2A | |
| SCHEMBL3719602 | 0.83 | SCN7A (0.34) | ACACBSCN9ASRC | |
| SCHEMBL3720615 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BACACBSCN9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |