Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.50 |
| ▸ | ACACA | Q13085 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723843 | 0.90 | PARP15 (0.41) | ACACBACACAPARP15PARP10MTNR1A | |
| SCHEMBL3720708 | 0.86 | MTNR1A (0.54) | ACACBACACACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3806067 | 0.85 | MTNR1A (0.44) | ACACBACACACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3722610 | 0.84 | ACACB (0.51) | ACACBACACACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3726867 | 0.83 | MTNR1A (0.50) | ACACBACACACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3721039 | 0.82 | ACACA (0.51) | ACACBACACAMTNR1AHTR2C | |
| SCHEMBL3726170 | 0.82 | KDM4E (0.50) | ACACB | |
| SCHEMBL3718635 | 0.81 | PPARA (0.45) | ACACBCYP2C9CYP1A2MTNR1A | |
| SCHEMBL3719665 | 0.80 | ACACB (0.54) | ACACBMTNR1A | |
| SCHEMBL3727291 | 0.80 | KDM4E (0.50) | ACACBMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |