Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | ACACB | O00763 | 6/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726867 | 0.93 | MTNR1A (0.50) | MTNR1AACACBACACAPTGDR2SMN1; SMN2 | |
| SCHEMBL3720443 | 0.86 | ACACB (0.50) | MTNR1AACACBACACAHTR2CCYP1A2 | |
| SCHEMBL3719665 | 0.83 | ACACB (0.54) | MTNR1AACACBSMN1; SMN2MTNR1B | |
| SCHEMBL3727291 | 0.82 | KDM4E (0.50) | MTNR1AACACBSMN1; SMN2MTNR1B | |
| SCHEMBL3722351 | 0.81 | SMN1; SMN2 (0.54) | MTNR1ASMN1; SMN2GAAMTNR1BMEN1 | |
| SCHEMBL3724749 | 0.81 | ACACB (0.45) | MTNR1AACACBPTGDR2SMN1; SMN2GAA | |
| SCHEMBL3720624 | 0.80 | ALDH1A1 (0.49) | MTNR1AACACBSMN1; SMN2HTR2CMTNR1B | |
| SCHEMBL3718635 | 0.79 | PPARA (0.45) | MTNR1AACACBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL3727221 | 0.79 | ACACB (0.45) | MTNR1AACACBSMN1; SMN2MTNR1B | |
| SCHEMBL3726170 | 0.79 | KDM4E (0.50) | ACACBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |