Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724474 | 0.76 | ESRRA (0.47) | HTTGAAL3MBTL1PPARAALDH1A1 | |
| SCHEMBL3724477 | 0.75 | PPARA (0.42) | HTTPPARAALDH1A1PPARGNPSR1 | |
| SCHEMBL3720490 | 0.75 | GLA (0.48) | PPARAPPARGCYP1A2 | |
| SCHEMBL3723729 | 0.74 | RORC (0.40) | HTTGAAHPGDATML3MBTL1 | |
| SCHEMBL28012956 | 0.73 | MRGPRX4 (0.46) | HTTHPGDATML3MBTL1PPARA | |
| SCHEMBL3717278 | 0.73 | CSNK2A1 (0.39) | HTTGAAHPGDATML3MBTL1 | |
| SCHEMBL3720848 | 0.73 | CYP17A1 (0.46) | CYP2C19CYP2C9CYP17A1 | |
| SCHEMBL3720850 | 0.73 | PPARA (0.43) | HPGDPPARAALDH1A1RAB9APPARG | |
| SCHEMBL3726843 | 0.72 | LTA4H (0.49) | GAAALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL3724597 | 0.72 | PPARA (0.41) | HTTPPARAALDH1A1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |