Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.37 |
| ▸ | ACACA | Q13085 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077252 | 0.84 | ACACB (0.46) | ACACBACACACYP3A4CYP2C9 | |
| SCHEMBL13076357 | 0.83 | ACACB (0.47) | ACACBACACACYP3A4CYP2C9 | |
| SCHEMBL3721287 | 0.82 | ACACA (0.51) | ACACBACACACYP3A4CYP2C9 | |
| SCHEMBL3718611 | 0.82 | TLR7 (0.37) | — | |
| SCHEMBL3724233 | 0.80 | ACACB (0.37) | ACACBACACACYP3A4CYP2C9MCHR1 | |
| SCHEMBL3724232 | 0.80 | PDE4B (0.46) | ACACBACACACYP3A4CYP2C9MCHR1 | |
| SCHEMBL3722669 | 0.80 | PARP10 (0.37) | MCHR1 | |
| SCHEMBL3717406 | 0.78 | ACACB (0.35) | ACACBACACACYP3A4CYP2C9 | |
| SCHEMBL3721927 | 0.78 | PARP10 (0.37) | ACACBACACACYP3A4CYP2C9MCHR1 | |
| SCHEMBL3722666 | 0.78 | MAOA (0.37) | ACACBACACACYP3A4CYP2C9MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |