Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721926 | 0.95 | PDE4B (0.44) | PDE4BACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3720427 | 0.89 | ACACB (0.56) | PDE4BACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3719578 | 0.87 | PDE4B (0.53) | PDE4BACACBACACAPARP15PARP10 | |
| SCHEMBL3721101 | 0.85 | PDE4B (0.44) | PDE4BACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3720755 | 0.85 | PDE4B (0.46) | PDE4BALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL3797155 | 0.84 | MTNR1A (0.42) | PDE4BACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3724295 | 0.84 | PDE4B (0.46) | PDE4BACACBMCHR1ALDH1A1GAA | |
| SCHEMBL3727011 | 0.83 | PDE4B (0.50) | PDE4BACACBPARP15PARP10PARP2 | |
| SCHEMBL3725384 | 0.83 | PDE4B (0.50) | PDE4BACACBCYP3A4ACACACYP2C9 | |
| SCHEMBL3726792 | 0.83 | PDE4B (0.45) | PDE4BMCHR1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |