Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717505 | 0.88 | KMT2A (0.40) | HTTALDH1A1PGK1SMN1; SMN2MEN1 | |
| SCHEMBL3725378 | 0.84 | ALDH1A1 (0.35) | ALDH1A1PGK1MEN1KMT2ATHRB | |
| SCHEMBL3720704 | 0.84 | PTGS1 (0.37) | ALDH1A1PGK1POLBMEN1KMT2A | |
| SCHEMBL3716943 | 0.82 | ALDH1A1 (0.34) | ALDH1A1PGK1ALOX15HPGDPPARG | |
| SCHEMBL3720677 | 0.80 | PTGS1 (0.34) | THRB | |
| SCHEMBL3986078 | 0.79 | LMNA (0.43) | HTTLMNAALDH1A1NPC1POLB | |
| SCHEMBL3719376 | 0.78 | KCNK3 (0.33) | PGK1PPARG | |
| SCHEMBL26231908 | 0.75 | WDR5 (0.35) | PGK1 | |
| SCHEMBL21823599 | 0.73 | ALDH1A1 (0.55) | HTTLMNAALDH1A1POLBMEN1 | |
| SCHEMBL3720178 | 0.72 | HPGD (0.46) | HTTLMNAALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |