Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718572 | 0.91 | PNLIP (0.40) | ACACBMAPTHPGDGAAHTT | |
| SCHEMBL3723729 | 0.91 | RORC (0.40) | ACACBMAPTHPGDGAAHTT | |
| SCHEMBL3725385 | 0.89 | MAPT (0.43) | ACACBMAPTHPGDGAAHTT | |
| SCHEMBL3718624 | 0.88 | ACACB (0.46) | ACACBMAPTHPGDGAAHTT | |
| SCHEMBL3720773 | 0.87 | P2RX3 (0.41) | ACACBMAPTHPGDGAAHTT | |
| SCHEMBL3717500 | 0.87 | MAPT (0.39) | MAPTATMKMT2AMEN1KDM4E | |
| SCHEMBL3717278 | 0.86 | CSNK2A1 (0.39) | MAPTHPGDGAAHTTATM | |
| SCHEMBL3719949 | 0.83 | RORC (0.39) | ACACBMAPTHPGDGAAHTT | |
| SCHEMBL3720733 | 0.81 | ACACB (0.39) | ACACBMAPT | |
| SCHEMBL3719337 | 0.81 | HPGD (0.38) | ACACBMAPTHPGDGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |