Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720773 | 0.92 | P2RX3 (0.41) | RORCP2RX3MAPTSMN1; SMN2ACACB | |
| SCHEMBL3720742 | 0.88 | MAPT (0.37) | P2RX3MAPTKCNH2ATML3MBTL1 | |
| SCHEMBL3718569 | 0.88 | MAPT (0.37) | P2RX3MAPTSMN1; SMN2KCNH2PGK1 | |
| SCHEMBL3723729 | 0.87 | RORC (0.40) | RORCMAPTKCNH2ACACBPGK1 | |
| SCHEMBL3717278 | 0.86 | CSNK2A1 (0.39) | CSNK2A1MAPTSMN1; SMN2CYP2C19KCNH2 | |
| SCHEMBL3726852 | 0.85 | P2RX3 (0.43) | P2RX3MAPTACACBGAAATM | |
| SCHEMBL3725385 | 0.83 | MAPT (0.43) | MAPTACACBGAAHPGDHTT | |
| SCHEMBL3720104 | 0.83 | ACACB (0.43) | RORCMAPTSMN1; SMN2ACACBGAA | |
| SCHEMBL3717014 | 0.82 | MAPT (0.34) | P2RX3MAPTSMN1; SMN2CYP2C19GAA | |
| SCHEMBL3720739 | 0.82 | MAPT (0.39) | P2RX3MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |