Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720396 | 0.90 | FFAR4 (0.50) | GAATAAR1MEN1KMT2AFFAR4 | |
| SCHEMBL3717666 | 0.85 | FFAR4 (0.44) | CYP1A2GAACYP2D6CYP2C19CYP3A4 | |
| SCHEMBL3717202 | 0.83 | ACACB (0.38) | CYP1A2GAACYP2D6CYP2C19CYP3A4 | |
| SCHEMBL7521694 | 0.82 | TAAR1 (0.61) | CYP1A2GAACYP2D6CYP2C19TAAR1 | |
| SCHEMBL3719900 | 0.81 | POLB (0.42) | CYP1A2GAACYP2D6CYP2C19LMNA | |
| SCHEMBL3720620 | 0.81 | ADRA2A (0.41) | CYP1A2GAACYP2D6CYP2C19TAAR1 | |
| SCHEMBL3717012 | 0.81 | TRPM8 (0.49) | TAAR1TAAR5 | |
| Hydrochloric Acid SCHEMBL14157113 | 0.80 | TAAR1 (0.59) | CYP1A2GAACYP2D6CYP2C19TAAR1 | |
| SCHEMBL3726846 | 0.80 | LTA4H (0.47) | CYP1A2CYP3A4TSHRNFKB1TAAR1 | |
| SCHEMBL3720760 | 0.79 | ALDH1A3 (0.45) | CYP1A2GAACYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |