Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.43 |
| ▸ | ACACA | Q13085 | 10/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804254 | 0.86 | TLR8 (0.39) | TLR8 | |
| SCHEMBL3720364 | 0.83 | NCF1 (0.38) | NCF1 | |
| SCHEMBL3722574 | 0.82 | SCN9A (0.36) | — | |
| SCHEMBL3720041 | 0.81 | MAP4K4 (0.48) | — | |
| SCHEMBL3724135 | 0.81 | ACACB (0.65) | ACACBACACA | |
| SCHEMBL3717959 | 0.80 | MAP4K4 (0.32) | NCF1 | |
| SCHEMBL3720891 | 0.79 | AKR1C3 (0.51) | — | |
| SCHEMBL3722382 | 0.79 | ALOX5 (0.35) | NCF1 | |
| SCHEMBL3720293 | 0.78 | GLA (0.42) | ACACBNCF1TLR8LTA4H | |
| SCHEMBL3728069 | 0.78 | ALOX5 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |